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Despite the risks, regulators have failed to set standards for indoor air quality – a problem that is now likely to be exacerbated by large numbers of people spending time inside and cooking at home during the coronavirus pandemic.
In the study of people aged over 55, published in Alzheimer's & Dementia, researchers found 'repetitive negative thinking' (RNT) is linked to subsequent cognitive decline as well as the deposition of harmful brain proteins linked to Alzheimer’s.
Depression affected a quarter of people with inflammatory bowel disease (IBD) and was independently linked to an increase in disease activity, according to study results published in Neurogastroenterology and Motility.
Mental Health, Physical Health | Four grams per day of omega-3 fatty acids, specifically eicosapentaenoic acid and docosahexaenoic acid together or eicosapentaenoic acid alone, is clinically useful as monotherapy or in addition to other therapies to reduce triglycerides after implementing diet and lifestyle changes and addressing any underlying causes, according to an American Heart Association science advisory published in Circulation.
Five of 6 anti-inflammatory agents were associated with improved depression scores in patients taking antidepressants, compared with adjunctive placebo.
Mental Health Update | The number of cannabis-associated emergency department (ED) visits has risen sharply since marijuana was legalized in Colorado.
New data show that although inhalable cannabis use accounts for most of these visits, edible cannabis is tied to a disproportionate number of visits, and patients present with different symptoms.
...but reports have generally focused on single disorders and are limited to first-degree relatives.
OBJECTIVES:
To examine family history of mental and neurological disorders among first- to fourth-degree relatives and risk of ASD with and without intellectual disability.
A family history of mental and/or neurological disorders was associated with a significant increased risk for autism spectrum disorder (ASD) with and without intellectual disability (ID). The closer the relative with the family history of mental and/or neurological disorders, the higher the ASD risk.
Why this matters
The association was stronger for ASD without ID, suggesting ASD without ID may be more familial than ASD with ID.
Study design
* 567,436 index persons who were non-adopted singleton births born between 1984 and 2009 and at least 2 years of age at the end of follow-up were included.
Key results
* Having ASD without (OR, 9.0; P<.0001) or with (OR, 3.8; P<.0001) ID affected vs unaffected first-degree relatives increased odds of ASD without ID in index persons.
* Having first-degree relative with cerebral palsy (P<.01), epilepsy (P<.0001), or migraine (P<.0001) increased odds of ASD without ID in index persons.
* A first-degree relative with ASD with (OR, 14.2; P<.0001) or without (OR, 4.1; P<.0001) ID increased odds of ASD with ID in index persons.
* A first-degree relative with cerebral palsy (P<.01) or epilepsy (P<.0001) doubled odds of ASD with ID in index persons.
The more closely related the affected family member was, the higher the odds was of ASD for the index person. ASD without intellectual disability was associated with more disorders compared to ASD with intellectual disability.
ASD with intellectual disability exhibited a weaker familial association with other mental disorder diagnoses but a stronger familial association with some neurological diagnoses as compared to ASD without intellectual disability.
Using data from the 2011 to 2016 National Vital Statistics System-Mortality files, the authors conducted a literal text analysis of death certificates to identify drugs mentioned as contributing to the cause of overdose death. They used this information to calculate which drugs were most frequently involved.
“Deaths involving more than 1 drug (eg, a death involving both heroin and cocaine) were counted in all relevant drug categories (eg, the same death was included in counts of heroin deaths and in counts of cocaine deaths),” the authors explained.
Results showed that between 2011 and 2016, the 10 drugs most frequently mentioned in relation to a drug overdose death were: fentanyl (ranked first in 2016), heroin (ranked first from 2012-2015), hydrocodone, methadone, morphine, oxycodone (ranked first in 2011), alprazolam, diazepam, cocaine (consistently ranked second or third), and methamphetamine.
During the study period, the age-adjusted rate of overdose deaths involving heroin and methamphetamine tripled, while the rate of overdose deaths involving methadone decreased (1.4 per 100,000 in 2011 to 1.1 in 2016). As for fentanyl and its analogs, between 2013 and 2016, the rate of overdose deaths doubled each year (0.6 per 100,000 in 2013 to 1.3 in 2014, 2.6 in 2015, and 5.9 in 2016).
Fentanyl, heroin, and cocaine were the most frequently mentioned drugs in overdose deaths that were considered unintentional, while oxycodone, diphenhydramine, hydrocodone, and alprazolam were more likely to be involved in cases of suicide. In addition, many of the overdose deaths were linked to use of multiple drugs.